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American Society of Microbiology ABMM Sample Questions (Q156-Q161):
NEW QUESTION # 156
A patient with a history of intravenous drug use develops a bloodstream infection with Enterococcus faecalis.
Antimicrobial susceptibility testing reveals resistance to vancomycin. The MOST likely mechanism of vancomycin resistance in Enterococcus involves:
- A. Increased expression of efflux pumps that actively transport vancomycin out of the cell.
- B. Alteration of the ribosomal target site, preventing vancomycin binding to the ribosome.
- C. Modification of the peptidoglycan precursor, reducing vancomycin binding.
- D. Production of enzymes that inactivate vancomycin.
Answer: C
NEW QUESTION # 157
The direct fluorescent antibody (DFA) test is commonly used for the rapid detection of which respiratory pathogen directly from nasopharyngeal specimens?
- A. Influenza virus
- B. Bordetella pertussis
- C. Legionella pneumophila (serogroup 1 in sputum)
- D. Mycoplasma pneumoniae
Answer: B
NEW QUESTION # 158
A patient undergoing chemotherapy for leukemia develops a severe pneumonia. Bronchoalveolar lavage fluid is examined, revealing numerous cysts containing crescent-shaped structures upon silver staining. The patient's CD4+ T-cell count is significantly low. The MOST likely diagnosis is infection with:
- A. Histoplasma capsulatum
- B. Blastomyces dermatitidis
- C. Pneumocystis jirovecii
- D. Coccidioides immitis
Answer: C
NEW QUESTION # 159
A patient with a history of heart valve replacement develops subacute bacterial endocarditis. Blood cultures grow a Gram-positive coccus that is alpha-hemolytic on blood agar, catalase-negative, and optochin-resistant.
The MOST likely organism is:
- A. Enterococcus faecalis
- B. Streptococcus pneumoniae
- C. Streptococcus pyogenes
- D. Viridans streptococci
Answer: D
NEW QUESTION # 160
Which serological marker pattern is most consistent with chronic Hepatitis B virus infection with high infectivity?
- A. HBsAg (-), Anti-HBs (+), Anti-HBc Total (+), IgM Anti-HBc (-), HBeAg (-), Anti-HBe (+)
- B. HBsAg (-), Anti-HBs (+), Anti-HBc Total (-), IgM Anti-HBc (-), HBeAg (-), Anti-HBe (-)
- C. HBsAg (+), Anti-HBs (-), Anti-HBc Total (+), IgM Anti-HBc (+), HBeAg (+), Anti-HBe (-)
- D. HBsAg (+), Anti-HBs (-), Anti-HBc Total (+), IgM Anti-HBc (-), HBeAg (+), Anti-HBe (-)
Answer: D
NEW QUESTION # 161
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